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These outcomes reflect the peptides broader roles in DNA stabilization and immune surveillance, alongside telomere maintenance

Some mechanistic hypotheses suggest that diabetic patients, due to altered gastric emptying, autonomic neuropathy, or baseline gastrointestinal dysmotility, may be more susceptible to the GI side effects associated with GLP-1 RAs

The patient has shown a reduction in BMI from baseline or has maintained the BMI reduction

Understanding which GLP-1 formulations are associated with lower rates of nausea is essential for both healthcare professionals and patients when selecting the most appropriate treatment option

Abbreviations: GLP-1, RAs

Hansen et al., 2015)